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Malat1 deficiency prevents neonatal heart regeneration

Malat1 deficiency prevents neonatal heart regeneration

Malat1 deficiency prevents neonatal heart regeneration The adult mammalian heart has limited regenerative capacity, while the neonatal heart fully regenerates after an insult during the first week of life. In this first week, heart regeneration is mainly driven by...
Mapping the hypertrophic heart, Nature Cardiovascular Research

Mapping the hypertrophic heart, Nature Cardiovascular Research

Nature Cardiovascular Research 2022: A human cell atlas of the pressure-inducedhypertrophic heart With a interdisciplinary team including clinical experts, bioinformaticians, and molecular biologists, we applied large-scale single-nuclei technologies to construct an...
Specific diagnosis and therapy for children with heart failure

Specific diagnosis and therapy for children with heart failure

Circulation 2021: Specific diagnosis and therapy for children with heart failure The pathological dilation of the heart muscle could have different characteristics in young patients and should therefore be treated individually. This is the result of a study conducted...