Top 15 Publications

Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction.  

Tombor LS, John D, Glaser SF, Luxán G, Forte E, Furtado M, Rosenthal N, Baumgarten N, Schulz MH, Wittig J, Rogg EM, Manavski Y, Fischer A, Muhly- Reinholz M, Klee K, Looso M, Selignow C, Acker T, Bibli SI, Fleming I, Patrick R, Harvey RP, Abplanalp WT, Dimmeler S. Nat Commun. 2021  doi: 10.1038/s41467-021-20905-1.
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Clonal Hematopoiesis-Driver DNMT3A Mutations Alter Immune Cells in Heart Failure.

Abplanalp WT, Cremer S, John D, Hoffmann J, Schuhmacher B, Merten M, Rieger MA, Vasa-Nicotera M, Zeiher AM, Dimmeler S. Circ Res. 2021 doi: 10.1161/CIRCRESAHA.120.317104
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The histone demethylase JMJD2B regulates endothelial-to- mesenchymal transition.

Glaser SF, Heumüller AW, Tombor L, Hofmann P, Muhly-Reinholz M, Fischer A, Günther S, Kokot KE, Hassel D, Kumar S, Jo H, Boon RA, Abplanalp W, John D, Boeckel JN, Dimmeler S. Proc Natl Acad Sci U S A. 2020  doi: 10.1073/pnas.1913481117
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Identification and Characterization of Hypoxia-Regulated Endothelial Circular RNA.

Long noncoding RNA MALAT1 regulates endothelial cell function and vessel growth.
Michalik KM, You X, Manavski Y, Doddaballapur A, Zörnig M, Braun T, John D, Ponomareva Y, Chen W, Uchida S, Boon RA, Dimmeler S.
Circulation research 2014; 11492014Apr25: 1389-97
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MicroRNA-34a regulates cardiac ageing and function.
Boon RA, Iekushi K, Lechner S, Seeger T, Fischer A, Heydt S, Kaluza D, Tréguer K, Carmona G, Bonauer A, Horrevoets AJ, Didier N, Girmatsion Z, Biliczki P, Ehrlich JR, Katus HA, Müller OJ, Potente M, Zeiher AM, Hermeking H, Dimmeler S.
Nature 2013; 49574392013Mar7: 107-10 >>
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Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs.
Hergenreider E, Heydt S, Tréguer K, Boettger T, Horrevoets AJ, Zeiher AM, Scheffer MP, Frangakis AS, Yin X, Mayr M, Braun T, Urbich C, Boon RA, Dimmeler S.
Nature cell biology 2012; 1432012: 249-56 >>
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Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase.
Guarani V, Deflorian G, Franco CA, Krüger M, Phng LK, Bentley K, Toussaint L, Dequiedt F, Mostoslavsky R, Schmidt MH, Zimmermann B, Brandes RP, Mione M, Westphal CH, Braun T, Zeiher AM, Gerhardt H, Dimmeler S, Potente M.
Nature 2011; 47373462011May12: 234-8 >>
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MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice.
Bonauer A, Carmona G, Iwasaki M, Mione M, Koyanagi M, Fischer A, Burchfield J, Fox H, Doebele C, Ohtani K, Chavakis E, Potente M, Tjwa M, Urbich C, Zeiher AM, Dimmeler S.
Science (New York, N.Y.) 2009; 32459352009Jun26: 1710-3 >>
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SIRT1 controls endothelial angiogenic functions during vascular growth.
Potente M, Ghaeni L, Baldessari D, Mostoslavsky R, Rossig L, Dequiedt F, Haendeler J, Mione M, Dejana E, Alt FW, Zeiher AM, Dimmeler S.
Genes & development 2007; 21202007Oct15: 2644-58 >>
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Transcoronary transplantation of progenitor cells after myocardial infarction.
Assmus B, Honold J, Schächinger V, Britten MB, Fischer-Rasokat U, Lehmann R, Teupe C, Pistorius K, Martin H, Abolmaali ND, Tonn T, Dimmeler S, Zeiher AM.
The New England journal of medicine 2006; 355122006Sep21: 1222-32 >>
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Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction.
Schächinger V, Erbs S, Elsässer A, Haberbosch W, Hambrecht R, Hölschermann H, Yu J, Corti R, Mathey DG, Hamm CW, Süselbeck T, Assmus B, Tonn T, Dimmeler S, Zeiher AM, .
The New England journal of medicine 2006; 355122006Sep21: 1210-21 >>
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Cathepsin L is required for endothelial progenitor cell-induced neovascularization.
Urbich C, Heeschen C, Aicher A, Sasaki K, Bruhl T, Farhadi MR, Vajkoczy P, Hofmann WK, Peters C, Pennacchio LA, Abolmaali ND, Chavakis E, Reinheckel T, Zeiher AM, Dimmeler S.
Nature medicine 2005; 1122005Feb: 206-13 >>
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Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells.
Aicher A, Heeschen C, Mildner-Rihm C, Urbich C, Ihling C, Technau-Ihling K, Zeiher AM, Dimmeler S.
Nature medicine 2003; 9112003Nov: 1370-6 >>
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Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69.
Haendeler J, Hoffmann J, Tischler V, Berk BC, Zeiher AM, Dimmeler S.
Nature cell biology 2002; 4102002Oct: 743-9 >>
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Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation.
Dimmeler S, Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM.
Nature 1999; 39967361999Jun10: 601-5 >>
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On this page you will find the publications from the Institute of Cardiovascular Regeneration. All publications are available directly under the PubMed Web.