nature communications 2021: Post-myocardial infarction heart failure dysregulates the bone vascular niche Clinicians and basic scientists from the Cardiology Department and Institute of Cardiovascular Regeneration described the response of the bone cell composition to...
Circulation 2021: Specific diagnosis and therapy for children with heart failure The pathological dilation of the heart muscle could have different characteristics in young patients and should therefore be treated individually. This is the result of a study conducted...
Circulation Research 2021: Clonal Hematopoiesis-Driver DNMT3A Mutations Alter Immune Cells in Heart Failure Clonal hematopoiesis driven by mutations of DNMT3A (DNA methyltransferase 3a) is associated with increased incidence of cardiovascular disease and poor...
Nature Communications: Endothelial cells show transient mesenchymal phenotype after infarct Endothelial cells show a remarkable plasticity after myocardial infarction and have critical roles in tissue adaption upon injury. In this study, appearing in Nature...
A research group from Goethe University and University Hospital Frankfurt was able to show that an inhibitor against microRNA-92a is effective in humans. The clinical study was supported by the German Center for Cardiovascular Research (DZHK). The microRNA therapy...
ACE2 is a protein on the surface of cells and serves as the entry gate for the SARS-CoV-2 coronavirus. A Frankfurt research group was able to show that ACE2 is significantly increased in tissue samples from patients with cardiovascular diseases. COVID-19 disease...
