Publications
Shumliakivska M, Luxán G, Hemmerling I, Scheller M, Li X, Müller-Tidow C, Schuhmacher B, Sun Z, Dendorfer A, Debes A, Glaser SF, Muhly-Reinholz M, Kirschbaum K, Hoffmann J, Nagel E, Puntmann VO, Cremer S, Leuschner F, Abplanalp WT, John D, Zeiher AM, Dimmeler S. Nat Commun. 2024; 15:606. doi: 10.1038/s41467-023-43003-w.
Aging impairs the neurovascular interface in the heart.
Wagner JUG, Tombor LS, Malacarne PF, Kettenhausen LM, Panthel J, Kujundzic H, Manickam N, Schmitz K, Cipca M, Stilz KA, Fischer A, Muhly-Reinholz M, Abplanalp WT, John D, Mohanta SK, Weber C, Habenicht AJR, Buchmann GK, Angendohr S, Amin E, Scherschel K, Klöcker N, Kelm M, Schüttler D, Clauss S, Günther S, Boettger T, Braun T, Bär C, Pham MD, Krishnan J, Hille S, Müller OJ, Bozoglu T, Kupatt C, Nardini E, Osmanagic-Myers S, Meyer C, Zeiher AM, Brandes RP, Luxán G, Dimmeler S. Science. 2023; 381:897-906. doi: 10.1126/science.ade4961.
Cell-intrinsic effects of clonal hematopoiesis in heart failure.
Abplanalp WT, Schuhmacher B, Cremer S, Merten M, Shumliakivska M, Macinkovic I, Zeiher AM, John D, Dimmeler S. Nat Cardiovasc Res. 2023;2:819–834. doi: 10.1038/s44161-023-00322-x.
The atlas of the hypertrophied heart.
Nicin, S. M. Schroeter, S. Glaser, R. Schulze-Brüning, M.-D. Pham, S. S. Hille, , K. Badder, W. T. Abplanalp, L. Tombor, O. J. Müller, M. Yekelchyk, T. Braun, B. Meder, C. Reich, M. Arsalan, T. Holubec, T. Walther, F. Emrich, J. Krishnan, A. M. Zeiher, D.John, Dimmeler S. Nat Cardiovasc Res. 2022. 1:174–185
Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction.
Tombor LS, John D, Glaser SF, Luxán G, Forte E, Furtado M, Rosenthal N, Baumgarten N, Schulz MH, Wittig J, Rogg EM, Manavski Y, Fischer A, Muhly-Reinholz M, Klee K, Looso M, Selignow C, Acker T, Bibli SI, Fleming I, Patrick R, Harvey RP, Abplanalp WT, Dimmeler S. Nat Commun. 2021 Jan 29;12(1):681. doi: 10.1038/s41467-021-20905-1.
Post-myocardial infarction heart failure dysregulates the bone vascular niche.
Hoffmann J, Luxán G, Abplanalp WT, Glaser SF, Rasper T, Fischer A, Muhly-Reinholz M, Potente M, Assmus B, John D, Zeiher AM, Dimmeler S. Nat Commun. 2021 Jun 25;12(1):3964. doi: 10.1038/s41467-021-24045-4.
Clonal Hematopoiesis-Driver DNMT3A Mutations Alter Immune Cells in Heart Failure.
Abplanalp WT, Cremer S, John D, Hoffmann J, Schuhmacher B, Merten M, Rieger MA, Vasa-Nicotera M, Zeiher AM, Dimmeler S. Circ Res. 2021 Jan 22;128(2):216-228.
The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition.
Glaser SF, Heumüller AW, Tombor L, Hofmann P, Muhly-Reinholz M, Fischer A, Günther S, Kokot KE, Hassel D, Kumar S, Jo H, Boon RA, Abplanalp W, John D, Boeckel JN, Dimmeler S. Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4180-4187
Stellos K, Gatsiou A, Stamatelopoulos K, Perisic Matic L, John D, Lunella FF, Jaé N, Rossbach O, Amrhein C, Sigala F, Boon RA, Fürtig B, Manavski Y, You X, Uchida S, Keller T, Boeckel JN, Franco-Cereceda A, Chen W, Schwalbe H, Bindereif A, Eriksson P, Maegdefessel L, Hedin U, Zeiher AM, Dimmeler S. Nat Med. 2016
MicroRNA-34a regulates cardiac ageing and function.
Boon RA, Iekushi K, Lechner S, Seeger T, Fischer A, Heydt S, Kaluza D, Tréguer K, Carmona G, Horrevoets AJ, Didier N, Girmatsion Z, Bonauer A, Biliczki P, Ehrlich JR, Katus HA, Müller OJ, Potente M, Zeiher AM, Hermeking H, Dimmeler S.
Nature 2013; 49574392013Mar7: 107-10
Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs.
Hergenreider E, Heydt S, Tréguer K, Boettger T, Horrevoets AJ, Zeiher AM, Scheffer MP, Frangakis AS, Yin X, Mayr M, Braun T, Urbich C, Boon RA, Dimmeler S.
Nature cell biology 2012; 1432012: 249-56
MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice.
Bonauer A, Carmona G, Iwasaki M, Mione M, Koyanagi M, Fischer A, Burchfield J, Fox H, Doebele C, Ohtani K, Chavakis E, Potente M, Tjwa M, Urbich C, Zeiher AM, Dimmeler S. Science (New York, N.Y.) 2009; 32459352009Jun26: 1710-3
Cathepsin L is required for endothelial progenitor cell-induced neovascularization.
Urbich C, Heeschen C, Aicher A, Sasaki K, Bruhl T, Farhadi MR, Vajkoczy P, Hofmann WK, Peters C, , Abolmaali ND, Chavakis E, Reinheckel T, Pennacchio LA, Zeiher AM, Dimmeler S. Nature medicine 2005; 1122005Feb: 206-13
Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells.
Aicher A, Heeschen C, Mildner-Rihm C, Urbich C, Ihling C, Technau-Ihling K, Zeiher AM, Dimmeler S.
Nature medicine 2003; 9112003Nov: 1370-6
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation.
Fleming I, Fisslthaler B, Hermann C, Busse R, Zeiher AM, Dimmeler S
Nature 1999; 39967361999Jun10: 601-5