Cardiovascular Repair and Regeneration
General scientific objectives:
The Institute for Cardiovascular Regeneration focuses on the identification of physiological and pathophysiological tissue repair and remodeling processes. Specifically, we aim to elucidate the contribution of the endothelium during vascular pathologies, e.g. atherosclerosis, or post-ischemic cardiac remodeling, partly driven by angiogenesis. In this context, improving vessel growth and maturation and as such modulating the healing under conditions like acute myocardial infarction is expected to contribute to an enhanced recovery of damaged tissue. To analyze and stimulate these mechanisms, the role of non-coding RNAs, epigenetic modulators and paracrine factors are currently focus of our research.